AOD-9604
Proper Handling
- Specifications: Lyophilized powder in 3 mL vial. Purity (>98%) meets or exceeds U.S. Pharmacopeia (USP) and National Formulary (USP-NF) regulations.
- Directions: Reconstitute with Bacteriostatic Water prior to use. Schedule a wellness consult or speak with your healthcare provider for proper dosage.
- Storage: In lyophilized form, the peptide is stable for 36 months. Protect from light. Refrigerate and use within 45 days after opening or reconstituting to prevent loss of potency.
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Schedule a consultation with a practitioner specialized in peptide therapy, who will review your medical history and determine the best plan for you.
Anti-Obesity Drug AOD-9604 may promote safe and effective weight loss by targeting areas of high-fat concentrations. AOD-9604 was used as an anti-obesity drug as it is a fragment of the growth hormone-releasing peptide (GHRP). By stimulating the pituitary gland, it helps the body regulate fat metabolism and reduce body fat.
AOD-9604 works by increasing metabolism while speeding up the fat-burning process. There have been many studies that also show that this peptide is highly effective for building muscle. There are two ways that the AOD-9604 peptide works. It can stimulate the release of excess fat from the fatty tissue while inhibiting more fat from building in the main area, being the mid-abdominal area.
CAS Number 221231-10-3
PubChem CID 16131447
Molecular Weight 1815.12g/mol
Molecular Formula C78H123N23O23S2
Synonyms AOD-9604; AOD 9604; AOD9604, Anti-Obesity Drug
Storage (Lyophilized)
At 39 Fahrenheit: 2 years
At -4 Fahrenheit: 3 years
is sold as a pure compound for research purposes only, unless prescribed by a licensed physician. This product comes in the form of lyophilized powder and must be reconstituted with bacteriostatic water prior to use. Please refer to our terms and conditions prior to purchase.
Safety Information: Keep this product out of the reach of children. This material has limited research available about it and may result in adverse effects if improperly handled or consumed. This product is not a dietary supplement, but a pure substance, sold as a raw material. We attest exclusively to the quality, purity and description of the materials we provide. This product is for use and handling only by persons with the knowledge and equipment to safely handle this material. You agree to indemnify us for any adverse effects that may arise from improper handling and/or consumption of this product.
The articles and information on products that may be found on this website are provided exclusively for the purposes of providing information and education. These items are not pharmaceuticals or medications, and the Food and Drug Administration has not given permission for the treatment or prevention of any disease, medical condition, or ailment using them.
- Mark Heffernan, Roger J. Summers, Anne Thorburn, Esra Ogru, Robert Gianello, Woei-Jia Jiang, Frank M. Ng, The Effects of Human GH and Its Lipolytic Fragment (AOD 9604) on Lipid Metabolism Following Chronic Treatment in Obese Mice and β 3-AR Knock-Out Mice, Endocrinology, Volume 142, Issue 12, 1 December 2001, Pages 5182–5189. https://pubmed.ncbi.nlm.nih.gov/11713213/
- Moré, M. I., & Kenley, D. (2014). Safety and metabolism of AOD9604, a novel nutraceutical ingredient for improved metabolic health. Journal of Endocrinology and Metabolism, 4(3), 64-77.
- Frank M. Ng, J Sun et.al, Metabolic Studies of a Synthetic Lipolytic Domain (AOD 9604) of Human Growth Hormone, Hormone Research, February 2000.
- News, Medical and Life Sciences, Obesity drug codenamed AOD 9604 highly successful in trials, 16 December 2004.
- Dong Rak Kwon and GI Young Park, Effect of Intra-articular Injection of AOD9604 with or without Hyaluronic Acid in Rabbit Osteoarthritis Model, Annals of Clinical and Laboratory Science, Volume 45, July-August 2015.
- Habibullah, M. M., Mohan, S., Syed, N. K., Makeen, H. A., Jamal, Q. M. S., Alothaid, H., Bantun, F., Alhazmi, A., Hakamy, A., Kaabi, Y. A., Samlan, G., Lohani, M., Thangavel, N., & Al-Kasim, M. A. (2022). Human Growth Hormone Fragment 176-191 Peptide Enhances the Toxicity of Doxorubicin-Loaded Chitosan Nanoparticles Against MCF-7 Breast Cancer Cells. Drug design, development and therapy, 16, 1963–1974. https://doi.org/10.2147/DDDT.S367586
Frequently Asked Questions
AOD-9604
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AOD-9604 is a modified form of amino acids 176-191 and was used as an anti-obesity drug. Once injected, this hormone derivative can stimulate the pituitary gland, which, in turn, speeds up metabolism and burns body fat.
This FDA-approved peptide therapy has the unique ability to target areas of the body with abnormally high levels of fat.
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- Body fat reduction
- Abdominal fat reduction
- Increases calorie burn
- Triggers fat release
- Increases metabolism
- Stabilizes blood sugar levels
- Regulates your appetite
- Contains regenerative properties
- May help with cartilage and bone repair, especially when paired with peptide BPC-157
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This is a common question, since most peptides once reconstituted are not cloudy. However, not all peptides are created equal!
AOD-9604 is a larger peptide, 16 amino acids, containing several hydrophobic residues. Hydrophobic molecules are literally “water- fearing”. HGH fragment is by far the most hydrophobic of any peptides.
The process in some labs includes using a copious amount of acetonitrile. To put this into perspective, when our peptides are being synthesized and tested for purity, a very small amount of acetonitrile is used to remove the impurities from a column that is being tested during the HPLC (.1% acetonitrile to be exact).
Now acetonitrile is a poisonous substance and needs to be removed from the final product (it metabolizes into cyanide). If this substance is not removed, the effects can be dangerous.
So, although this is very counter-intuitive, the fact that your AOD-9604 is cloudy tells you that it is true HGH Fragment, and that it does not contain copious amounts of acetonitrile.
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AOD-9604 is an injectable peptide administered subcutaneously through the fat. The most fatty parts of the body are the abdomen, side or back of upper arms, and front of thighs.
AOD-9604 is for research purposes only, unless prescribed by a licensed physician. Schedule a telehealth appointment or talk to a specialist to determine the best plan for your health.
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AOD-9604 is commonly injected subcutaneously, making its use at risk for local redness, irritation, itching and swelling of the injection site.
Other noted side effects from clinical studies included:
- Headache
- Chest tightness
- Palpitations
- Feelings of euphoria
While these side effects were rare, it is important to consult with a medical professional prior to starting AOD-9604.
Remember, everyone reacts differently to substances like AOD-9604 due to individual physiological differences such as metabolism rate and overall health status. Talk to your healthcare provider about any side effect that bothers you or doesn’t go away. Tell your doctor if you have any side effects.
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Anti-Obesity Peptide AOD-9604 is a peptide naturally produced in our body as a part of the human growth hormone (HGH). AOD-9604 was assigned GRAS status by the FDA, which stands for Generally Recognized As Safe when used as intended.
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We're happy to help answer questions you may have, or refer you to a licensed healthcare professional for medical advice. Email us at care@somapeptides.com or schedule a wellness consultation.
Your body, your journey .
Millions of people want to know how peptide therapy can help achieve achieve optimal health and performance.
Speak with licensed physicians and specialists in peptide therapy about proper dosage, reconstituting lyophilized peptides, titrating up (or down), and proper care and consideration of your medical history.