TB-500
Proper Handling
- Specifications: Lyophilized powder in 3 mL vial. Purity (>98%) meets or exceeds U.S. Pharmacopeia (USP) and National Formulary (USP-NF) regulations.
- Directions: Reconstitute with Bacteriostatic Water prior to use. Schedule a wellness consult or speak with your healthcare provider for proper dosage.
- Storage: In lyophilized form, the peptide is stable for 36 months. Protect from light. Refrigerate and use within 45 days after opening or reconstituting to prevent loss of potency.
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TB-500 is a synthetic peptide of a protein that all humans have in their bodies. The natural protein occurs in cells and is called Thymosin Beta 4. This protein may have healing properties.
TB-500 may help speed up injury recovery. Some injuries and wounds could take several months or longer to heal on their own, TB-500 peptide may reduce that time.
CAS Number 885340-08-9
PubChem CID 62707662
Molecular Weight 889.0 g/mol
Molecular Formula C38H68N10O14
Synonyms TB500; TB 500; TB-500; L-Glutamine
Storage (Lyophilized)
At 39 Fahrenheit: 2 years
At -4 Fahrenheit: 3 years
is for research purposes only, unless prescribed by a licensed physician. Schedule a telehealth appointment to determine the best plan for your health. This product comes in the form of lyophilized powder and must be reconstituted with bacteriostatic water prior to use. Please refer to our terms and conditions prior to purchase.
Safety Information: Keep this product out of the reach of children. This material has limited research available about it and may result in adverse effects if improperly handled or consumed. This product is not a dietary supplement, but a pure substance, sold as a raw material. We attest exclusively to the quality, purity and description of the materials we provide. This product is for use and handling only by persons with the knowledge and equipment to safely handle this material. You agree to indemnify us for any adverse effects that may arise from improper handling and/or consumption of this product.
The articles and information on products that may be found on this website are provided exclusively for the purposes of providing information and education. These items are not pharmaceuticals or medications, and the Food and Drug Administration has not given permission for the treatment or prevention of any disease, medical condition, or ailment using them.
- Kleinman HK, Sosne G. Thymosin β4 Promotes Dermal Healing. Vitam Horm. 2016;102:251-75. doi: 10.1016/bs.vh.2016.04.005. Epub 2016 May 24.
- Julia Parmley, A Life-Saving Discovery, January 04, 2010.
- Gurtner GC, Werner S, Barrandon Y, Longaker MT. Wound repair and regeneration. Nature. 2008 May 15;453(7193):314-21. doi: 10.1038/nature07039. PMID: 18480812.
- Ho EN, Kwok WH, Lau MY, Wong AS, Wan TS, Lam KK, Schiff PJ, Stewart BD. Doping control analysis of TB-500, a synthetic version of an active region of thymosin β₄, in equine urine and plasma by liquid chromatography-mass spectrometry. J Chromatogr A. 2012 Nov 23;1265:57-69. doi: 10.1016/j.chroma.2012.09.043. Epub 2012 Sep 23.
- Katherine M. Malinda et.al, Thymosin β4 Accelerates Wound Healing, Journal of Investigative Dermatology, Volume 113, Issue 3, 1999, Pages 364-368, ISSN 0022-202X.
- Treadwell T, Kleinman HK, Crockford D, Hardy MA, Guarnera GT, Goldstein AL. The regenerative peptide thymosin β4 accelerates the rate of dermal healing in preclinical animal models and in patients. Ann N Y Acad Sci. 2012 Oct.
- Wei C, Kim IK, Li L, Wu L, Gupta S. Thymosin Beta 4 protects mice from monocrotaline-induced pulmonary hypertension and right ventricular hypertrophy. PLoS One. 2014 Nov 20;9(11):e110598.
- Gao, Xy., Hou, F., Zhang, Zp. et al. Role of thymosin beta 4 in hair growth. Mol Genet Genomics 291, 1639–1646 (2016).
- Esposito S, et al. Synthesis and characterization of the N-terminal acetylated 17-23 fragment of thymosin beta 4 identified in TB-500, a product suspected to possess doping potential. Drug Test Analysis. 2012 Sep.
- Piao Z, Hong CS, Jung MR, Choi C, Park YK. Thymosin β4 induces invasion and migration of human colorectal cancer cells through the ILK/AKT/β-catenin signaling pathway. Biochem Biophys Res Commun. 2014 Sep 26;452(3):858-64.
- Study of Thymosin Beta 4 in Patients with Pressure Ulcers https://www.clinicaltrials.gov/ct2/show/NCT00382174
- A Phase 2 study of the effect of Thymosin Beta 4 on Wound Healing in Patients https://www.clinicaltrials.gov/ct2/show/NCT00311766
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Frequently Asked Questions
TB-500 Peptide
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TB-500 is a synthetic version of the healing protein released by the thymus gland (Thymosin Beta 4). That, in turn, creates T-cells which work to boost the immune system to fight off disease; plus, heals damage to the tendons, muscles, ligaments, and bones.
Thymosin Beta 4 also reduces inflammation, increases collagen, and determines how well we recover from injuries.
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Research has shown that TB-500 substantially aids in the recovery and healing of injuries that would typically take months to heal, such as tendonitis, ligament damage, and fractures. Its regenerative properties have also been recognized in various kinds of heart tissue.
TB-500 offers potential help to promote wound healing, decrease inflammation, and recover faster from surgeries or illnesses.
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TB-500 is an injectable peptide administered subcutaneously through the fat. The most fatty parts of the body are the abdomen, side or back of upper arms, and front of thighs.
This peptide is for research purposes only, unless prescribed by a licensed physician. Schedule a wellness consultation to determine the best plan for your health.
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TB-500 is not approved by the FDA for human consumption. The only exceptions are for researchers and doctors who can purchase or prescribe TB-500 under certain conditions.
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In the case of TB-500, the side effects appear to be mild. The most common side effects include:
- face flushing
- possible headache
- dizziness
- lethargy
The boost to the immune system may have some contraindications for people with auto-immune diseases, such as psoriasis, Hashimoto’s, and rheumatoid arthritis.
Remember, everyone reacts differently to substances like TB-500 due to individual physiological differences such as metabolism rate and overall health status. Consult with a licensed healthcare professional if you are considering peptide therapy.
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We're happy to help answer questions you may have, or refer you to a licensed healthcare professional for medical advice. Email us at care@somapeptides.com or schedule a telehealth appointment.
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